GM-CSF Protéine
Aperçu rapide pour GM-CSF Protéine (ABIN935394)
Antigène
Voir toutes GM-CSF (CSF2) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
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Attributs du produit
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Purified recombinant Human GM-CSF protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is 1.0 x 10^8 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from 10 mM tris, pH 8.5.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Autre désignation
- GM-CSF
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Sujet
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GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.
Alternative Names: Granulocyte/Macrophage Colony-Stimulating Factor protein, MGI-1GM protein, GM-CSF protein, CSF-2 protein, pluripoietin-alpha protein -
Poids moléculaire
- 14.5 kDa
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Pathways
- Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin
Antigène
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